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Alzheimer’s Gene Found

A report just posted at CNN says that scientists have found a strong link between a particular gene and Alzheimer’s.

The study, released Sunday on the Web site of the journal Nature Genetics, focused on Alzheimer’s that appears after age 65, the most common type.

Only one gene, called APOE, has been firmly linked to raising susceptibility to the common form. A Harvard-based group lists about 20 other genes it considers promising candidates, based on research.

Some authors of the new paper said they believe the evidence for SORL1 is unusually strong.

Experts familiar with the new work said SORL1 probably is involved in Alzheimer’s, but cautioned that it will be important for other scientists to confirm that.

“People will jump on it pretty fast,” said Rudy Tanzi of Harvard Medical School.

Gerard Schellenberg of the University of Washington said the paper’s evidence is “pretty solid, so I’m optimistic that it will be replicated.”

I’d love to tell you I checked out the article from Nature, but I’m having trouble finding it.

I’ll update this when I find it.

Filed under: Biology, Science, Science Links

3 Responses

  1. Good news. All of my great uncles and aunts (minus one) contracted the disease. My grandfather actually used to go to Duke Medical every 6 months for blood tests and when he died he donated his brain for study because he was the only one (and one brother) out of 9 siblings and a few of their other relatives that didn’t have Alzheimers.

  2. JanieBelle says:

    Yep, Rev. Good news indeed.

    It runs sporadically on my mother’s side, and seems to really go for the women in particular.

    It worries me.

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